Boc-N-amido-PEG3-acid
Boc-N-amido-PEG3-acid is a polyethylene glycol (PEG) spacer used in constructing PROTAC molecules. It connects a target-binding ligand to an E3 ligase recruiter, facilitating intracellular protein degradation via the ubiquitin-proteasome system. This linker is widely applied in both in vitro biochemical assays and in vivo proof-of-concept studies for targeted protein degradation research.
Product Specifications
CAS Number
1347750-75-7
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O (C (NCCOCCOCCOCCC (O) =O) =O) C (C) (C) C
Molecular Formula
C14H27NO7
Molecular Weight
321.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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