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9-Decyn-1-ol

9-Decyn-1-ol is a PROTAC linker used to conjugate GDC-0068 and Lenalidomide into the degrader INY-03-041. This compound is a potent, selective pan-Akt degrader with IC50 values of 2.0, 6.8, and 3.5 nM against Akt1, Akt2, and Akt3, respectively, and is a valuable tool for targeted protein degradation research in oncology.

Product Specifications

CAS Number

17643-36-6

Field of Research

Pharmacology & Drug Discovery

Smiles

C (CCCC#C) CCCCO

Molecular Formula

C10H18O

Molecular Weight

154.25

Storage Conditions

-20°C

Notes

For research use only.

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