SB 203580 hydrochloride
SB 203580 hydrochloride is a selective p38 MAPK inhibitor that also affects kinases like GSK3β and induces autophagy. It has been used in antiretroviral therapy research and has shown efficacy in reducing neuropathic pain in mouse models, making it a tool for studying inflammation and neurodegeneration.
Product Specifications
CAS Number
869185-85-3
Product Name Alternative
Adezmapimod hydrochloride, LCK, p38 MAPK, p38, p38MAPK, SB203580 hydrochloride, SB-203580 Hydrochloride, RWJ 64809 hydrochloride, RWJ64809 hydrochloride
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
97.79% (May vary between batches)
Solubility
H2O:2 mg/mL (4.83 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.83 mM) ; DMSO:84.17 mg/mL (203.36 mM)
Smiles
Cl.O=S (C=1C=CC (=CC1) C2=NC (C=3C=CN=CC3) =C (N2) C=4C=CC (F) =CC4) C
Molecular Formula
C21H17ClFN3OS
Molecular Weight
413.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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