SG3199
SG3199 is a potent PBD dimer that covalently binds the DNA minor groove to form interstrand cross-links. This mechanism underlies its significant cytotoxicity against diverse human cancer cell lines in vitro, supporting its investigation as a payload in antibody-drug conjugates for oncology research.
Product Specifications
CAS Number
1595275-71-0
Field of Research
Molecular Biology
Smiles
[H][C@@]12CC (C) =CN1C (=O) c1cc (OC) c (OCCCCCOc3cc4N=C[C@]5 ([H]) CC (C) =CN5C (=O) c4cc3OC) cc1N=C2
Molecular Formula
C33H36N4O6
Molecular Weight
584.66
Storage Conditions
-20°C
Notes
For research use only.
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