N2-iso-Butyroyl-5'-O-DMT-3'-O- (methoxyethyl) guanosine

This is a 3'-O- (methoxyethyl) -modified guanosine nucleoside derivative, featuring an N2-iso-butyroyl protecting group and a 5'-O-DMT protection while keeping the amino and hydroxyl groups open. It serves as a key synthetic intermediate in oligonucleotide chemistry, particularly for constructing antisense oligonucleotides and siRNAs for in vitro and in vivo therapeutic research.