BIRM 271
BIRM 271 is a potent, enantiomerically pure inhibitor of arachidonic acid release, effectively suppressing the biosynthesis of leukotriene B4 (IC50 = 40 nM) and platelet-activating factor in human neutrophils. This small molecule is a valuable research tool for studying eicosanoid signaling in inflammation, applicable in both in vitro cellular assays and in vivo models of inflammatory diseases.
Product Specifications
CAS Number
149106-77-4
Product Name Alternative
BIRM271, BIRM-271, BIRM 271, LTB4, Phospholipase
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.38% (May vary between batches)
Solubility
DMSO:50 mg/mL (149.06 mM)
Smiles
N ([C@H] (CC1CCCCC1) C2=CC=CC=N2) C=3OC=4C (N3) =CC (C) =CC4
Molecular Formula
C21H25N3O
Molecular Weight
335.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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