N6-Methyl-2'-O-methyladenosine
N6,2′-O-Dimethyladenosine (m6Am) is a reversible RNA modification serving as a substrate for the obesity-linked enzyme FTO. This small molecule is a valuable research tool for studying epitranscriptomic mechanisms in metabolic diseases, applicable in both in vitro and cell-based assays.
Product Specifications
CAS Number
57817-83-1
Product Name Alternative
Analog, FTO, N6,2′-O-Dimethyladenosine, N6-Methyl-2'-O-methyladenosine, NucleosideAntimetabolite, Nucleoside Antimetabolite/Analog, Nucleoside Antimetabolite
Field of Research
Cell Biology, Molecular Biology
Purity
99.77% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (8.47 mM) ; DMSO:55 mg/mL (186.26 mM)
Smiles
O (C) [C@H]1[C@H] (N2C=3C (N=C2) =C (NC) N=CN3) O[C@H] (CO) [C@H]1O
Molecular Formula
C12H17N5O4
Molecular Weight
295.29
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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