Clozapine N-oxide dihydrochloride
Clozapine N-oxide dihydrochloride is a blood-brain barrier permeable agonist for the chemogenetic DREADD receptors hM3Dq and hM4Di. It is a key research tool for targeted neuronal manipulation in studies of neural circuits, behavior, and diseases, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2250025-93-3
Product Name Alternative
AChE, Clozapine N-oxide, Clozapine N-oxide Dihydrochloride
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
98.11% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (24.05 mM) ; H2O:50 mg/mL (120.27 mM) ; DMSO:200 mg/mL (481.07 mM)
Smiles
C[N+]1 (CCN (C2=NC3=CC (Cl) =CC=C3NC4=C2C=CC=C4) CC1) [O-].Cl.Cl
Molecular Formula
C18H21Cl3N4O
Molecular Weight
415.74
Storage Conditions
-20°C
Notes
For research use only.
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