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Clozapine N-oxide dihydrochloride

Clozapine N-oxide dihydrochloride is a blood-brain barrier permeable agonist for the chemogenetic DREADD receptors hM3Dq and hM4Di. It is a key research tool for targeted neuronal manipulation in studies of neural circuits, behavior, and diseases, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2250025-93-3

Product Name Alternative

AChE, Clozapine N-oxide, Clozapine N-oxide Dihydrochloride

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

98.11% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (24.05 mM) ; H2O:50 mg/mL (120.27 mM) ; DMSO:200 mg/mL (481.07 mM)

Smiles

C[N+]1 (CCN (C2=NC3=CC (Cl) =CC=C3NC4=C2C=CC=C4) CC1) [O-].Cl.Cl

Molecular Formula

C18H21Cl3N4O

Molecular Weight

415.74

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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