Larotinib mesylate hydrate
Larotinib mesylate hydrate is a potent and orally bioavailable tyrosine kinase inhibitor with broad-spectrum activity, notably targeting EGFR with high potency (IC50 = 0.6 nM) . It is widely used in preclinical research for investigating EGFR-driven cancers, demonstrating efficacy in both in vitro cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
2097129-93-4
Field of Research
Cardiovascular Research, Immunology & Inflammation, Signal Transduction
Smiles
CS (=O) (O) =O.COC (C (OCCCN1C[C@]2 ([H]) [C@] (OCCO2) ([H]) C1) =C3) =CC4=C3C (NC5=CC (Cl) =C (C=C5) F) =NC=N4.CS (=O) (O) =O.O
Molecular Formula
C26H36ClFN4O11S2
Molecular Weight
699.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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