PF-06815345 hydrochloride
PF-06815345 hydrochloride is a potent, orally bioavailable small molecule inhibitor of PCSK9 with an IC50 of 13.4 μM. It is a valuable research tool for studying PCSK9 biology and lipid metabolism, having demonstrated efficacy in reducing PCSK9 levels in mouse models.
Product Specifications
CAS Number
2334434-49-8
Smiles
CN1C (=C (C=N1) C2=C (F) C=C (C (N (C3=C (Cl) C=CC=N3) [C@@H]4CCCNC4) =O) C=C2) C=5N ([C@@H] (OC (OCC) =O) C) N=NN5.Cl
Molecular Formula
C27H30Cl2FN9O4
Molecular Weight
634.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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