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PF-06815345 hydrochloride

PF-06815345 hydrochloride is a potent, orally bioavailable small molecule inhibitor of PCSK9 with an IC50 of 13.4 μM. It is a valuable research tool for studying PCSK9 biology and lipid metabolism, having demonstrated efficacy in reducing PCSK9 levels in mouse models.

Product Specifications

CAS Number

2334434-49-8

Smiles

CN1C (=C (C=N1) C2=C (F) C=C (C (N (C3=C (Cl) C=CC=N3) [C@@H]4CCCNC4) =O) C=C2) C=5N ([C@@H] (OC (OCC) =O) C) N=NN5.Cl

Molecular Formula

C27H30Cl2FN9O4

Molecular Weight

634.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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