PI3K/mTOR Inhibitor-12
PI3K/mTOR Inhibitor-12 is a potent, orally bioavailable small molecule with high selectivity, exhibiting IC50 values of 0.06 nM against PI3Kα and 3.12 nM against mTOR. It demonstrates significant antitumor efficacy in preclinical models, supported by in vitro cell proliferation assays and in vivo xenograft studies, while showing a favorable toxicity profile with reduced liver toxicity.
Product Specifications
CAS Number
2891692-83-2
Field of Research
Pharmacology & Drug Discovery; Cell Biology, Signal Transduction
Smiles
COC1=C (C=C (C=N1) C2=NN3C (=NC=C3C4=CN (N=N4) CCCN5CCOCC5) C=C2) NS (=O) (=O) C6=C (C=C (C=C6) F) F
Molecular Formula
C27H27F2N9O4S
Molecular Weight
611.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
