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LEM-14-1189

LEM-14-1189 is a potent, pan-NSD inhibitor targeting NSD1, NSD2, and NSD3 with respective IC50 values of 418 μM, 111 μM, and 60 μM. This compound exhibits potential anticancer activity and is a useful research tool for studying hematological malignancies, including multiple myeloma, in both cellular and animal models.

Product Specifications

CAS Number

2987501-17-5

Product Name Alternative

NSD, Histone Methyltransferase, HistoneMethyltransferase

Field of Research

Epigenetics & Chromatin

Purity

97.98% (May vary between batches)

Solubility

DMSO:6.84 mg/mL (10.02 mM)

Smiles

C1CCC2=C (C1) C3=C (S2) N=C (NC3=O) CN (CCCNC (=O) C4=CC5=CC=CC=C5C (=O) O4) CC6=NC7=C (C8=C (S7) CCCC8) C (=O) N6

Molecular Formula

C35H34N6O5S2

Molecular Weight

682.81

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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