LEM-14-1189
LEM-14-1189 is a potent, pan-NSD inhibitor targeting NSD1, NSD2, and NSD3 with respective IC50 values of 418 μM, 111 μM, and 60 μM. This compound exhibits potential anticancer activity and is a useful research tool for studying hematological malignancies, including multiple myeloma, in both cellular and animal models.
Product Specifications
CAS Number
2987501-17-5
Product Name Alternative
NSD, Histone Methyltransferase, HistoneMethyltransferase
Field of Research
Epigenetics & Chromatin
Purity
97.98% (May vary between batches)
Solubility
DMSO:6.84 mg/mL (10.02 mM)
Smiles
C1CCC2=C (C1) C3=C (S2) N=C (NC3=O) CN (CCCNC (=O) C4=CC5=CC=CC=C5C (=O) O4) CC6=NC7=C (C8=C (S7) CCCC8) C (=O) N6
Molecular Formula
C35H34N6O5S2
Molecular Weight
682.81
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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