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C-Met-IN-14

C-Met-IN-14 is a potent and selective N-sulfonylamidine-based c-Met kinase inhibitor (IC50 = 2.89 nM) . It exerts anticancer effects by blocking c-Met phosphorylation, inducing G2/M cell cycle arrest, and promoting apoptosis in A549 cells in vitro, making it a valuable tool for oncology research.

Product Specifications

CAS Number

2443380-34-3

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

O (C=1C2=C (C=C (OCCCN3CCOCC3) C (OC) =C2) N=CC1) C4=C (F) C=C (N=C (NS (CC5=CC=C (Cl) C=C5) (=O) =O) CCOC) C=C4

Molecular Formula

C34H38ClFN4O7S

Molecular Weight

701.2

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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