DOCK2-IN-1
DOCK2-IN-1 is a cell-permeable inhibitor that targets the DHR-2 domain of DOCK2 (IC50 = 19.1 μM), blocking Rac activation downstream of chemokine and antigen receptors. This action suppresses lymphocyte chemotaxis and T-cell activation, making it a useful tool for studying immune cell migration and signaling in both in vitro and in vivo immunological research models.
Product Specifications
CAS Number
4590-86-7
Purity
99.93% (May vary between batches)
Smiles
O=C1NN (C=2C=CC=CC2) C (=O) C1=CC=3C=CC=CC3Cl
Molecular Formula
C16H11ClN2O2
Molecular Weight
298.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
IRBAMLENTPD7AP395200UL 200 µL
Rabbit Anti ENTPD7 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (IHC,ELISA) 200ul
Sign In for Pricing
View Details K4487308 1.0 µg DNA
Exosc10 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
Sign In for Pricing
View Details 27545126 3x 1.0µg DNA
LOXL4 CRISPRa sgRNA lentivector (set of three targets)(Rat)
Sign In for Pricing
View Details 
AFG-ELL-2139 > 5x 10^5 Cells / Vial
Mouse Internal Anal Sphincter Smooth Muscle Cells
Sign In for Pricing
View Details