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DOCK2-IN-1

DOCK2-IN-1 is a cell-permeable inhibitor that targets the DHR-2 domain of DOCK2 (IC50 = 19.1 μM), blocking Rac activation downstream of chemokine and antigen receptors. This action suppresses lymphocyte chemotaxis and T-cell activation, making it a useful tool for studying immune cell migration and signaling in both in vitro and in vivo immunological research models.

Product Specifications

CAS Number

4590-86-7

Purity

99.93% (May vary between batches)

Smiles

O=C1NN (C=2C=CC=CC2) C (=O) C1=CC=3C=CC=CC3Cl

Molecular Formula

C16H11ClN2O2

Molecular Weight

298.72

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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