BTK-IN-22
BTK-IN-22 is a potent and selective small molecule inhibitor of BTK (IC50: 0.9 nM), with additional activity against BLX and BMX. It demonstrates superior kinase selectivity compared to Ibrutinib. This inhibitor is a valuable chemical probe for studying B-cell signaling pathways in both cellular and biochemical assays.
Product Specifications
CAS Number
2573048-10-7
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
NC1=C2C (=NN (C2=NC=N1) [C@H]3CN (C (C=C) =O) CCC3) C4=C (C) C=C (OC5=CC=CC=C5) C=C4
Molecular Formula
C26H26N6O2
Molecular Weight
454.52
Storage Conditions
-20°C
Notes
For research use only.
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