(R) -ZG197
(R) -ZG197 is a selective small-molecule activator of Caseinolytic protease P (ClpP) . It potently activates Staphylococcus aureus ClpP (EC50 = 1.5 μM) and, with lower potency, human ClpP (EC50 = 31.4 μM) . This compound is a valuable research tool for studying bacterial proteostasis and virulence in vitro and for exploring ClpP's role as a potential antibacterial target.
Product Specifications
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Smiles
C[C@H] (C1=C2C (C=CC=C2) =CC=C1) N3C[C@] (N4[C@@H] ([C@@H] (C) CC) C3=O) ([H]) N (C (NCCCC (F) (F) F) =O) CCC4=O
Molecular Formula
C28H35F3N4O3
Molecular Weight
532.6
Storage Conditions
-20°C
Notes
For research use only.
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