MSC-1186
MSC-1186 is a potent, pan-SRPK inhibitor with high selectivity, exhibiting IC50 values of 2.7 nM (SRPK1), 81 nM (SRPK2), and 0.6 nM (SRPK3) . Its application in cancer research includes studying aberrant RNA splicing in vitro and demonstrating antitumor efficacy in preclinical in vivo models.
Product Specifications
CAS Number
2871698-23-4
Field of Research
Cell Biology, Metabolism Research
Smiles
N (CC1=C (N (S (C) (=O) =O) C) N=CC=C1) C2=NC (C=3NC=4C (N3) =CC=C (Cl) C4F) =NC=C2
Molecular Formula
C19H17ClFN7O2S
Molecular Weight
461.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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