CFT8634
CFT8634 is a potent and selective BRD9 PROTAC degrader that functions by recruiting an E3 ligase to ubiquitinate and eliminate BRD9 protein. It demonstrates anti-proliferative activity in SMARCB1-deficient cell lines in vitro and has shown efficacy in relevant in vivo xenograft models, supporting its use in oncology research targeting BRD9-dependent cancers.
Product Specifications
CAS Number
2704617-96-7
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
99.95% (May vary between batches)
Smiles
CC=1C (C2=CC (OC) =C (CN3CC (F) (F) [C@H] (CC3) N4CCN (CC4) C5=C (F) C=C (N[C@@H]6C (=O) NC (=O) CC6) C=C5) C (OC) =C2) =CN (C) C (=O) C1C
Molecular Formula
C37H45F3N6O5
Molecular Weight
710.79
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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