TNG908
TNG908 is an orally bioavailable, brain-penetrant small molecule that selectively inhibits the MTAP-co-PRMT5 complex. It is a research tool for targeting MTAP-deleted cancers, demonstrating potent anti-tumor activity in both cellular assays and in vivo models.
Product Specifications
CAS Number
2760481-53-4
Product Name Alternative
Histone Methyltransferase, HistoneMethyltransferase, PRMT5
Field of Research
Epigenetics & Chromatin
Purity
98.08% (May vary between batches)
Solubility
DMSO:80 mg/mL (195.36 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (8.06 mM)
Smiles
C (C (NC=1C=C (C) C (N) =NC1) =O) (=O) N2[C@H] (CC[C@H] (C) C2) C=3C=C4C (=CC3) SC=N4
Molecular Formula
C21H23N5O2S
Molecular Weight
409.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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