DMUP
DMUP is a small molecule CD47-SIRPα axis inhibitor that demonstrates potent antitumor activity. It promotes apoptosis and enhances macrophage-mediated phagocytosis in A549 cells while downregulating CD47 and SIRPα protein expression. This compound is a valuable research tool for studying innate immune checkpoint blockade in oncology, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2364350-07-0
Field of Research
Cell Biology
Smiles
O=C1OC=2C=C (OCC (=O) [O-][Pt+4] ([Cl-]) ([Cl-]) ([O-]C (=O) COC=3C=CC4=C (OC (=O) C=C4C) C3) ([NH3]) [NH3]) C=CC2C (=C1) C
Molecular Formula
C24H24Cl2N2O10Pt
Molecular Weight
766.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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