BAY-069
BAY-069 is a novel (trifluoromethyl) pyrimidinedione-based chemical probe that potently inhibits BCAT1 (IC50=31 nM) and BCAT2 (IC50=153 nM) . This inhibitor is a valuable tool for investigating the role of branched-chain amino acid metabolism in cancer biology, supporting both in vitro and in vivo anticancer research.
Product Specifications
CAS Number
2639638-66-5
Product Name Alternative
BCAT, BAY 069, BAY069, BAY-069, Reactive Oxygen Species, ReactiveOxygenSpecies
Field of Research
Immunology & Inflammation, Metabolism Research, Signal Transduction
Purity
98.83% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (61.55 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.19 mM)
Smiles
O=C1N (C=2C3=C (C (Cl) =C (OC4=C (C) C=CC=C4) C2) C=CC=C3) C (=O) NC (C (F) (F) F) =C1
Molecular Formula
C22H14ClF3N2O3
Molecular Weight
446.81
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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