AZD-6918
AZD6918 is a potent and selective inhibitor of Trk tyrosine kinases. It blocks BDNF/TrkB-mediated protection against etoposide and inhibits TrkB-driven cell migration and growth in neuroblastoma models, as demonstrated in both in vitro and in vivo studies. This makes it a valuable research tool for investigating Trk signaling in oncology and neurobiology.
Product Specifications
CAS Number
905585-60-6
Field of Research
Signal Transduction
Smiles
N ([C@@H] (C) C1=CC=C (F) C=C1) C2=C (C#N) C=C (F) C (NC=3C=C (OC (C) C) NN3) =N2
Molecular Formula
C20H20F2N6O
Molecular Weight
398.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
494000 100 µL
TMED1 (Transmembrane Emp24 Domain-Containing Protein 1, Transmembrane Emp24 Protein Transport Domain Containing 1)
Sign In for Pricing
View Details MBS9425290-01 96 Tests
Human Alpha-N-acetylglucosaminidase ELISA Kit
Sign In for Pricing
View Details MBS9425290-02 5x 96 Tests
Human Alpha-N-acetylglucosaminidase ELISA Kit
Sign In for Pricing
View Details 
BIO0188SM-5mg 5 mg
Anti-human ICOS / CD278 (Vopratelimab Biosimilar)
Sign In for Pricing
View Details VAng-Ly2148-500gEcoli 500 µg (E. coli)
Recombinant Campylobacter Jejuni glyA Protein (aa 1-414) (strain 81116 / NCTC 11828)
Sign In for Pricing
View Details