AZD-6918
AZD6918 is a potent and selective inhibitor of Trk tyrosine kinases. It blocks BDNF/TrkB-mediated protection against etoposide and inhibits TrkB-driven cell migration and growth in neuroblastoma models, as demonstrated in both in vitro and in vivo studies. This makes it a valuable research tool for investigating Trk signaling in oncology and neurobiology.
Product Specifications
CAS Number
905585-60-6
Field of Research
Signal Transduction
Smiles
N ([C@@H] (C) C1=CC=C (F) C=C1) C2=C (C#N) C=C (F) C (NC=3C=C (OC (C) C) NN3) =N2
Molecular Formula
C20H20F2N6O
Molecular Weight
398.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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