Porfiromycin
Porfiromycin, an N-methyl derivative of mitomycin C, is a bioreductive antibiotic that alkylates DNA and generates oxygen radicals, causing interstrand cross-links and single-strand breaks to inhibit DNA synthesis. Its selective toxicity toward hypoxic cells makes it a valuable tool for researching tumor hypoxia, DNA damage mechanisms, and combination therapies in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
801-52-5
Field of Research
Molecular Biology
Smiles
O (C) [C@]12N (C3=C ([C@H]1COC (N) =O) C (=O) C (N) =C (C) C3=O) C[C@]4 ([C@@]2 (N4C) [H]) [H]
Molecular Formula
C16H20N4O5
Molecular Weight
348.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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