AZD4877 HCl
AZD4877 is a selective kinesin spindle protein (KSP/Eg5) inhibitor that disrupts mitotic spindle formation, leading to mitotic arrest and apoptosis in proliferating tumor cells. Its mechanism, distinct from tubulin-targeting agents, may reduce neurotoxicity risks. It is used in cancer research, with studies demonstrating its activity in both in vitro cell assays and in vivo xenograft models.
Product Specifications
CAS Number
758722-12-2
Field of Research
Metabolism Research
Smiles
Cl.CC (C) C (N (CCCN) C (=O) c1ccc (C) cc1) c1nc2snc (C) c2c (=O) n1Cc1ccccc1
Molecular Formula
C28H34ClN5O2S
Molecular Weight
540.123
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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