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AZD4877 HCl

AZD4877 is a selective kinesin spindle protein (KSP/Eg5) inhibitor that disrupts mitotic spindle formation, leading to mitotic arrest and apoptosis in proliferating tumor cells. Its mechanism, distinct from tubulin-targeting agents, may reduce neurotoxicity risks. It is used in cancer research, with studies demonstrating its activity in both in vitro cell assays and in vivo xenograft models.

Product Specifications

CAS Number

758722-12-2

Field of Research

Metabolism Research

Smiles

Cl.CC (C) C (N (CCCN) C (=O) c1ccc (C) cc1) c1nc2snc (C) c2c (=O) n1Cc1ccccc1

Molecular Formula

C28H34ClN5O2S

Molecular Weight

540.123

Storage Conditions

-20°C

Notes

For research use only.

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