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Iso-Fludelone

Iso-Fludelone is a third-generation epothilone B analog with potent antineoplastic activity. It stabilizes microtubules, inhibits cell division, and induces apoptosis, while exhibiting improved pharmacokinetics and circumventing P-glycoprotein-mediated drug resistance. It is applied in cancer research for in vitro cytotoxicity assays and in vivo tumor model studies.

Product Specifications

CAS Number

691868-19-6

Field of Research

Signal Transduction

Smiles

C (=C\C=1C=C (C) ON1) (\C) /[C@@H]2C/C=C (\C (F) (F) F) /C/C=C/[C@H] (C) [C@H] (O) [C@@H] (C) C (=O) C (C) (C) [C@@H] (O) CC (=O) O2

Molecular Formula

C27H36F3NO6

Molecular Weight

527.57

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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