Iso-Fludelone
Iso-Fludelone is a third-generation epothilone B analog with potent antineoplastic activity. It stabilizes microtubules, inhibits cell division, and induces apoptosis, while exhibiting improved pharmacokinetics and circumventing P-glycoprotein-mediated drug resistance. It is applied in cancer research for in vitro cytotoxicity assays and in vivo tumor model studies.
Product Specifications
CAS Number
691868-19-6
Field of Research
Signal Transduction
Smiles
C (=C\C=1C=C (C) ON1) (\C) /[C@@H]2C/C=C (\C (F) (F) F) /C/C=C/[C@H] (C) [C@H] (O) [C@@H] (C) C (=O) C (C) (C) [C@@H] (O) CC (=O) O2
Molecular Formula
C27H36F3NO6
Molecular Weight
527.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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