Caricotamide
Caricotamide is a synthetic activator of the human enzyme NQO2, which is overexpressed in several cancers. When used with the prodrug tretazicar, it enables the generation of a DNA cross-linking agent, inhibiting replication and inducing apoptosis. This mechanism supports its investigation as a chemoadjuvant in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
64881-21-6
Smiles
C (C (N) =O) N1C=C (C (N) =O) CC=C1
Molecular Formula
C8H11N3O2
Molecular Weight
181.19
Storage Conditions
-20°C
Notes
For research use only.
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