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ABE171

NVP-ABE171 is a potent, pan-PDE4 inhibitor with anti-inflammatory properties. It demonstrates nanomolar activity in vitro by suppressing oxidative bursts and cytokine release from human immune cells, and shows in vivo efficacy in animal models of lung inflammation by inhibiting airway neutrophil influx.

Product Specifications

CAS Number

426268-06-6

Smiles

C (O) (=O) C1=CC=C (C=2N=C (C3=C (C2) C=CC=N3) C4=CC=5C (C=C4) =NON5) C=C1

Molecular Formula

C21H12N4O3

Molecular Weight

368.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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