ABE171
NVP-ABE171 is a potent, pan-PDE4 inhibitor with anti-inflammatory properties. It demonstrates nanomolar activity in vitro by suppressing oxidative bursts and cytokine release from human immune cells, and shows in vivo efficacy in animal models of lung inflammation by inhibiting airway neutrophil influx.
Product Specifications
CAS Number
426268-06-6
Smiles
C (O) (=O) C1=CC=C (C=2N=C (C3=C (C2) C=CC=N3) C4=CC=5C (C=C4) =NON5) C=C1
Molecular Formula
C21H12N4O3
Molecular Weight
368.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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