PHA-680626
PHA-680626 is a potent, selective PLK inhibitor with additional activity against Bcr-Abl and Aurora kinases. It demonstrates anti-proliferative and pro-apoptotic effects in Imatinib-resistant CML models, including cell lines and primary CD34+ cells, supporting its research use in oncology and kinase signaling pathways.
Product Specifications
CAS Number
398493-74-8
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction
Smiles
N (C (=O) C1=CC=C (C=C1) N2CCN (C) CC2) C=3C4=C (CN (C (CC5=CC=CS5) =O) C4) NN3
Molecular Formula
C23H26N6O2S
Molecular Weight
450.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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