PARG-IN-4
PARG-IN-4 (Compound A) is a potent, cell-permeable, and orally bioavailable PARG inhibitor with an EC50 of 1.9 nM. This small molecule demonstrates antitumor efficacy in mouse models and is a valuable chemical probe for studying PARP biology, DNA repair mechanisms, and cancer therapeutics in both in vitro and in vivo research.
Product Specifications
CAS Number
2988890-20-4
Field of Research
Cell Biology
Purity
98.51% (May vary between batches)
Solubility
DMSO:16 mg/mL (32.15 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.02 mM)
Smiles
S (NC1 (C) CC1) (=O) (=O) C=2C=C3C (=C (C2) N4C[C@H] (C) N[C@@H] (C) C4) C=NN3C=5SC (C (F) F) =NN5
Molecular Formula
C20H25F2N7O2S2
Molecular Weight
497.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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