Cis-4-Hydroxy-L-proline

Cis-4-Hydroxy-L-proline is an inhibitor of the synthesis and extracellular deposition of collagen. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. (In Vivo) :cis-4-Hydroxy-L-proline depressed the growth of primary N-nitrosomethylurea-induced rat mammary tumors.