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5'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite

This product is a nucleoside phosphoramidite monomer used in the solid-phase synthesis of oligonucleotides. It is specifically designed to incorporate a 2'-O-methyl and N6-methyl adenosine modification, which enhances nuclease resistance and alters binding affinity, making it valuable for in vitro and in vivo applications in antisense and siRNA therapeutic research.

Product Specifications

CAS Number

2348385-04-4

Field of Research

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Smiles

C (OC[C@@H]1[C@@H] (OP (N (C (C) C) C (C) C) OCCC#N) [C@@H] (OC) [C@@H] (O1) N2C=3C (N=C2) =C (NC) N=CN3) (C4=CC=C (OC) C=C4) (C5=CC=C (OC) C=C5) C6=CC=CC=C6

Molecular Formula

C42H52N7O7P

Molecular Weight

797.88

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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