Eleven-Nineteen-Leukemia Protein IN-3
Eleven-Nineteen-Leukemia Protein IN-3 is a potent, orally bioavailable inhibitor of the ENL YEATS domain with an IC50 of 15.4 nM. It downregulates MYC expression in cells and stabilizes the ENL protein in vitro, making it a valuable chemical probe for researching transcriptional regulation in cancers like leukemia.
Product Specifications
CAS Number
2894121-83-4
Field of Research
Cancer Biology, Epigenetics & Chromatin
Smiles
C[C@H]1CCCN1CC1=NC2=CC (NC (=O) C3=CC=C4C (=C3) C3=CC=CC=C3C (=O) N4C) =CC=C2N1
Molecular Formula
C28H27N5O2
Molecular Weight
465.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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