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Eleven-Nineteen-Leukemia Protein IN-3

Eleven-Nineteen-Leukemia Protein IN-3 is a potent, orally bioavailable inhibitor of the ENL YEATS domain with an IC50 of 15.4 nM. It downregulates MYC expression in cells and stabilizes the ENL protein in vitro, making it a valuable chemical probe for researching transcriptional regulation in cancers like leukemia.

Product Specifications

CAS Number

2894121-83-4

Field of Research

Cancer Biology, Epigenetics & Chromatin

Smiles

C[C@H]1CCCN1CC1=NC2=CC (NC (=O) C3=CC=C4C (=C3) C3=CC=CC=C3C (=O) N4C) =CC=C2N1

Molecular Formula

C28H27N5O2

Molecular Weight

465.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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