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Y-27632 HCl hydrate

Y-27632 HCl hydrate is an orally active, ATP-competitive inhibitor of ROCK1/ROCK2. It inhibits caspase-3 activity and suppresses stem cell apoptosis, making it a valuable reagent for improving the survival and generation efficiency of induced pluripotent stem cells (iPSCs) in both in vitro culture and in vivo transplantation studies.

Product Specifications

CAS Number

331752-47-7

Product Name Alternative

Y 27632, Y27632, Y-27632, Y27632 hydrochloride hydrate

Field of Research

Cell Biology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.98% (May vary between batches)

Smiles

O=C ([C@H]1CC[C@] (CC1) ([H]) [C@H] (N) C) NC2=CC=NC=C2.Cl.O.Cl

Molecular Formula

C14H25Cl2N3O2

Molecular Weight

338.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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