APBC
APBC is a potent small-molecule inhibitor of PD-L1, disrupting the PD-1/PD-L1 axis with low-micromolar affinity. It demonstrates significant antitumor activity in a humanized PD-L1 mouse melanoma model and shows no observable hepatotoxicity, supporting its utility for immune-oncology research in both cellular and animal studies.
Product Specifications
CAS Number
324054-99-1
Smiles
N (C (=O) C1=CC=C (C=C1) C2=CC=CC=C2) C3=C (C (N) =O) C=CC=C3
Molecular Formula
C20H16N2O2
Molecular Weight
316.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb3077550 100 µg
Syntaxin 1a/STX1A Rabbit Polyclonal Antibody (Carrier-free)
Sign In for Pricing
View Details 
MBS1444993-01 0.02 mg (E-Coli)
Recombinant Staphylococcus aureus UPF0291 protein SACOL1376 (SACOL1376)
Sign In for Pricing
View Details