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APBC

APBC is a potent small-molecule inhibitor of PD-L1, disrupting the PD-1/PD-L1 axis with low-micromolar affinity. It demonstrates significant antitumor activity in a humanized PD-L1 mouse melanoma model and shows no observable hepatotoxicity, supporting its utility for immune-oncology research in both cellular and animal studies.

Product Specifications

CAS Number

324054-99-1

Smiles

N (C (=O) C1=CC=C (C=C1) C2=CC=CC=C2) C3=C (C (N) =O) C=CC=C3

Molecular Formula

C20H16N2O2

Molecular Weight

316.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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