APBC
APBC is a potent small-molecule inhibitor of PD-L1, disrupting the PD-1/PD-L1 axis with low-micromolar affinity. It demonstrates significant antitumor activity in a humanized PD-L1 mouse melanoma model and shows no observable hepatotoxicity, supporting its utility for immune-oncology research in both cellular and animal studies.
Product Specifications
CAS Number
324054-99-1
Smiles
N (C (=O) C1=CC=C (C=C1) C2=CC=CC=C2) C3=C (C (N) =O) C=CC=C3
Molecular Formula
C20H16N2O2
Molecular Weight
316.35
Storage Conditions
-20°C
Notes
For research use only.
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