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DBRD4-BD1

DBRD4-BD1 is a selective BRD4 bromodomain degrader (DC50 = 280 nM) that uniquely upregulates BRD2/3, distinguishing it from pan-BET degraders. Its selectivity facilitates precise BRD4 biology studies in vitro and enables the design of novel heterobifunctional probes for targeted protein degradation research.

Product Specifications

CAS Number

2839318-19-1

Field of Research

Epigenetics & Chromatin, Immunology & Inflammation, Pharmacology & Drug Discovery

Smiles

O (C=1N=C (C2=C (N=CN2C3CCN (CCOCCOCCNC (COC4=C5C (C (=O) N (C5=O) C6C (=O) NC (=O) CC6) =CC=C4) =O) CC3) C7=CC=C (C (F) (F) F) C=C7) C=CN1) C8=CC (C (C) C) =CC=C8C

Molecular Formula

C50H53F3N8O9

Molecular Weight

967

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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