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Suzetrigine

Suzetrigine (VX-548) is a selective, orally bioavailable inhibitor of the NaV1.8 sodium channel. It is a research tool for investigating acute pain mechanisms and neurotransmission, with applications in both in vitro electrophysiology studies and in vivo preclinical models of pain.

Product Specifications

CAS Number

2649467-58-1

Product Name Alternative

Nav1.8 channel, Sodium Channel, SodiumChannel, Suzetrigine, VX 548, VX548, VX-548

Field of Research

Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

DMSO:161 mg/mL (340.1 mM)

Smiles

C (NC=1C=C (C (N) =O) N=CC1) (=O) [C@H]2[C@@H] ([C@H] (C) [C@@] ([C@@] (F) (F) F) (C) O2) C3=C (OC) C (F) =C (F) C=C3

Molecular Formula

C21H20F5N3O4

Molecular Weight

473.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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