SK-575
SK-575 is a small molecule degradation agent that selectively targets and degrades PARP1 chimera proteins. It demonstrates potent anticancer activity, particularly in BRCA1/2-mutant cancer cells, by inhibiting proliferation in vitro and showing efficacy in relevant tumor models in vivo.
Product Specifications
CAS Number
2523016-96-6
Product Name Alternative
SK 575, SK575, SK-575, PARP1
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.39% (May vary between batches)
Solubility
DMSO:80 mg/mL (91.22 mM)
Smiles
O=C1NN=C (C=2C=CC=CC12) CC3=CC=C (F) C (=C3) C (=O) N4CCN (C (=O) CCCCCCCCCCC (=O) NCCNC5=CC=CC=6C (=O) N (C (=O) C56) C7C (=O) NC (=O) CC7) CC4
Molecular Formula
C47H53FN8O8
Molecular Weight
876.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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