BR103354
BR103354 is a potent and selective fibroblast activation protein (FAP) inhibitor with an IC50 of 14 nM. It demonstrates anti-diabetic and anti-steatotic effects in vivo, enhancing the activity of hFGF21 in ob/ob mice, and shows favorable pharmacokinetics for research into metabolic diseases like NASH.
Product Specifications
CAS Number
2505339-87-5
Smiles
C (CNC (=O) C=1N=C (CC2=CC=C (C#N) C=C2) SC1) (=O) N3[C@H] (C#N) CC (F) (F) C3
Molecular Formula
C19H15F2N5O2S
Molecular Weight
415.42
Storage Conditions
-20°C
Notes
For research use only.
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