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BR103354

BR103354 is a potent and selective fibroblast activation protein (FAP) inhibitor with an IC50 of 14 nM. It demonstrates anti-diabetic and anti-steatotic effects in vivo, enhancing the activity of hFGF21 in ob/ob mice, and shows favorable pharmacokinetics for research into metabolic diseases like NASH.

Product Specifications

CAS Number

2505339-87-5

Smiles

C (CNC (=O) C=1N=C (CC2=CC=C (C#N) C=C2) SC1) (=O) N3[C@H] (C#N) CC (F) (F) C3

Molecular Formula

C19H15F2N5O2S

Molecular Weight

415.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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