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TG11-77 HCl

TG11-77 HCl is a potent, selective, and brain-permeable EP2 receptor antagonist with a Schild KB of 9.7 nM. Its favorable solubility, pharmacokinetics, and brain exposure make it a valuable second-generation tool compound for investigating EP2-mediated pathways in neurological and inflammatory disease models, both in vitro and in vivo.

Product Specifications

CAS Number

2490544-34-6

Smiles

C (CNC (=O) C=1C=NC (NC2=CC (C) =CC (C) =N2) =NC1) C=3C=4C (NC3C) =CC=CC4.Cl

Molecular Formula

C23H24N6O.xHCl

Molecular Weight

436.944

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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