PSB-KD477
PSB-KD477 is a potent and selective synthetic agonist for the orphan receptor GPR18, demonstrating superior activity to THC in β-arrestin recruitment assays without activating CB1, CB2, or GPR55. Its distinct indole-based structure makes it a valuable chemical probe for validating GPR18's physiological roles in vitro and for exploring its involvement in immune regulation and cancer biology, as suggested by preliminary research.
Product Specifications
CAS Number
2488763-19-3
Smiles
O=C1C=2N3C (=NC2N (C) C (=O) N1C) N (CCC=4C=5C (NC4) =CC=CC5) CCCC3
Molecular Formula
C21H24N6O2
Molecular Weight
392.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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